Clinicopathological presentation of COVID-19 patients presented at the rural healthcare center

Clinicopathological presentation of COVID-19 patients

Abstract

The current observational cross-sectional study was conducted to determine hematological anomalies in young (below 50 years old) and elderly (above 50 years old) patients that were suffering from coronavirus diseases-2019 (COVID-19) reported at an outpatient clinic in the rural healthcare center from 1^st May 2021 to 31^st August 2021. A total of 100 patients reported in the above-mentioned time frame were included in the current study, which were confirmed with diagnosis of COVID-19 infection by real time polymerase chain reaction (RT-PCR) using a nasopharyngeal swab (NPS). Data were collected on demographic factors, sign & symptoms, comorbidity status, and hematological parameters. A total of 100 COVID-19 positive patients were enrolled in this study with a mean age 49 years. The majority 66 (66%) of participants were male with a mean body mass index (BMI) of 26. In addition, the cough was the most prevailing symptom 74 (74%), followed by fever 68 (68%), shortness of breath 60 (60%), and absence of taste/smell 3 (3%), respectively. Also, diabetes was the most prevalent comorbidity 44 (44%), after that hypertension 33 (33%), ischemic heart disease 17 (17%), urinary tract infection 8 (8%), and chronic kidney disease 1 (1%), respectively. The bifurcations of hematological factors of COVID-19 positive patients with respect to age groups were also presented. This work determined that the hematological, coagulative, and inflammatory markers are the utmost important parameters in predicting the management, treatment, and prognostication of COVID-19 infection.